Anti-quorum sensing and biofilm inhibitory activity of Apium graveolens L. oleoresin.


J Food Sci Technol. 2020 Jul ;57(7):2414-2422. Epub 2020 Jan 28. PMID: 32549591

Abstract Title: 

Anti-quorum sensing and biofilm inhibitory activity ofL. oleoresin.


L. (Apiaceae) is a dietary herb used as a spice, condiment and medicine.(Celery) has been studied for its antimicrobial property and for its application as flavours in food industry. The present study investigated theoleoresin as an anti-quorum sensing and antibiofilm agent. The quorum sensing and biofilm inhibition study was carried out using biosensor strainsCV12472 andPAO1. The MIC of celery oleoresin againstCV12472 andPAO1 was 10 and 25% v/v, respectively. Inhibition of violacein and biofilm formation was tested at concentrations of oleoresins ranging from 1.56 and 50% v/v. The oleoresins showed a concentration dependent QS inhibitory activity and at sub-MIC of 6.25 and 12.5% v/v, the oleoresins significantly inhibited violacein production and biofilm formation ( 

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